Vista normal Vista MARC

Biodegradation of NSAIDs and their effect on the activity of ligninolytic enzymes from Pleurotus djamor

Cruz Ornelas, Rosbi | Sánchez, José E [autor/a] | Amaya Delgado, Lorena [autor/a] | Guillén Navarro, Griselda Karina [autor/a] | Calixto Romo, Angeles [autor/a].
Tipo de material: Artículo en línea Artículo en línea Tema(s): Pleurotus djamor | Biodegradación | Diclofenaco | Naproxeno | Ketoprofeno | Enzimas ligninolíticas | EnzimologíaTema(s) en inglés: Pleurotus djamor | Biodegradation | Diclofenac | Naproxen | Ketoprofen | Ligninolytic enzymes | EnzymologyNota de acceso: Acceso en línea sin restricciones En: 3 Biotech. volumen 9, no 10, 373 (October 2019), páginas 1-8. --ISSN: 2190-5738Número de sistema: 59658Resumen:
Inglés

In this work, the white-rot fungus Pleurotus djamor was used for the first time to determine the degradation kinetics of the nonsteroidal anti-inflammatory drugs diclofenac, naproxen and, ketoprofen, either individually or in mixtures, in submerged cultures. Removal of 93% individual diclofenac and 99% diclofenac in mixtures with naproxen and ketoprofen at 6 h of incubation with the fungus was achieved. The elimination levels of naproxen and ketoprofen individually were 90% and 87%, respectively, after 48 h of incubation. However, the removal levels of these compounds in mixtures were 85% and 83%, respectively. On the other hand, during the degradation kinetics analysis, the enzymatic activities of laccases, manganese peroxidases, and lignin peroxidases were evaluated, yielding values of 3700, 270 and 31 U/L, respectively. Additionally, it was demonstrated that during degradation of diclofenac or the three drugs mixed in the submerged cultures, the enzymatic activity of extracellular laccases expressed by P. djamor increased by 200% and 300%, respectively. The activity of manganese peroxides increased by 126% with diclofenac and 138% when the mixture of drugs was added to the cultures. On the other hand, lignin peroxidase only increased activity by 123% with the drug mixture.

Recurso en línea: https://link.springer.com/article/10.1007%2Fs13205-019-1904-4
Etiquetas de esta biblioteca: No hay etiquetas de esta biblioteca para este título. Ingresar para agregar etiquetas.
Star ratings
    Valoración media: 0.0 (0 votos)
Existencias
Tipo de ítem Biblioteca actual Colección Signatura Estado Fecha de vencimiento Código de barras
Artículos Biblioteca Electrónica
Recursos en línea (RE) 		ECOSUR Recurso digital ECO400596581436

Acceso en línea sin restricciones

In this work, the white-rot fungus Pleurotus djamor was used for the first time to determine the degradation kinetics of the nonsteroidal anti-inflammatory drugs diclofenac, naproxen and, ketoprofen, either individually or in mixtures, in submerged cultures. Removal of 93% individual diclofenac and 99% diclofenac in mixtures with naproxen and ketoprofen at 6 h of incubation with the fungus was achieved. The elimination levels of naproxen and ketoprofen individually were 90% and 87%, respectively, after 48 h of incubation. However, the removal levels of these compounds in mixtures were 85% and 83%, respectively. On the other hand, during the degradation kinetics analysis, the enzymatic activities of laccases, manganese peroxidases, and lignin peroxidases were evaluated, yielding values of 3700, 270 and 31 U/L, respectively. Additionally, it was demonstrated that during degradation of diclofenac or the three drugs mixed in the submerged cultures, the enzymatic activity of extracellular laccases expressed by P. djamor increased by 200% and 300%, respectively. The activity of manganese peroxides increased by 126% with diclofenac and 138% when the mixture of drugs was added to the cultures. On the other hand, lignin peroxidase only increased activity by 123% with the drug mixture. eng

Disponible en línea

Adobe Acrobat profesional 6.0 o superior

Con tecnología Koha