Modern solid state fermentation: theory and practice / Hongzhang Chen

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1 Introduction.. 1.1 Solid-State Fermentation.. 1.1.1 Solid-State Fermentation Connotation.. 1.1.2 The Difference Between Solid-State Fermentation and Liquid Fermentation.. 1.1.3 Advantages and Applications of Solid-State Fermentation.. 1.2 Principles and Regulations of Modern Solid-State Fermentation.. 1.2.1 Solid-State Fermentation Process Regulation Based on Biological Characteristics.. 1.2.2 Solid-State Fermentation Process Regulation Based on Substrate Characteristics.. 1.3 Development of Solid-State Fermentation Engineering.. 1.3.1 Upstream Engineering of Solid-State Fermentation.. 1.3.2 Solid-State Fermentation Midstream Engineering.. 1.3.3 Solid-State Fermentation Downstream Engineering and Auxiliary Technology.. References.. 2 Biotechnology Principles of Solid State Fermentation.. 2.1 Overview of the Microbial Physiology of Solid-State Fermentation.. 2.1.1 Microbial Growth and Metabolic Characteristics.. 2.1.2 Characteristics of the Solid-State Fermentation Interface and Their Impacts on Microbial Metabolism.. 2.1.3 Filamentous Microorganisms on the Solid Matrix.. 2.1.4 Bacterial Growth on the Solid Matrix.. 2.1.5 Yeast Growth on a Solid Matrix.. 2.1.6 Numerical Simulation of Solid-State Fermentation by Nutritional Carrier Matrix Based on Segmentation and Integration.. 2.2 Properties of the Solid Matrix in Solid-State Fermentation.. 2.2.1 Types of Solid Matrix Suitable for Solid-State Fermentation.. 2.2.2 Pretreatment of Solid Matrix for Solid-State Fermentation.. 2.2.3 Material Parameters Affecting Solid-State Fermentation.. 2.3 Aseptic Techniques and Inoculation Techniques for Large-Scale Solid-State Fermentation.. 2.3.1 Large-Scale Aseptic Techniques for Solid-State Fermentation.. 2.3.2 Inoculation Technology for Solid-State Fermentation.. References.. 3 Principles of Solid-State Fermentation Engineering and Its Scale-Up.. 3.1 The Essence of Solid-State Fermentation

3.1.1 The Relationship Between the Three-Phase Ratio in Fermentation and Microbial Physiology.. 3.1.2 Characteristics and Roles of the Matrix Gas Phase in Solid-State Fermentation.. 3.1.3 The Roles of the Evapotranspiration Process in Solid-State Fermentation.. 3.2 Solid-State Fermentation Transfer Principle.. 3.2.1 Introduction to Heat and Mass Transfer in Solid-State Fermentation.. 3.2.2 Theoretical Basis of Heat, Moisture, and Solute Transfer Processes.. 3.2.3 Physical Parameters Affect the Solid Matrix Transfer Process.. 3.2.4 Changes in Nutritional Carrier Transfer Properties During Cell Growth.. 3.3 Thermal Physics Phenomenon in Solid Substrate Covered by Organisms.. 3.3.1 Microorganism-Matrix System Transfer Problems.. 3.3.2 Effect of Microbial Growth on the Matrix Heat Transfer Process.. 3.3.3 Effect of Microbial Growth on Matrix Moisture and Oxygen Transfer.. 3.3.4 Effect of Microbial Growth on the Solid Matrix.. 3.4 Design and Scale-Up of Solid-State Fermentation Bioreactors.. 3.4.1 Solid-State Fermentation Bioreactors.. 3.4.2 Factors that Influence Bioreactor Design.. 3.4.3 The Principle of Scale-Up of a Solid-State Fermentation Bioreactor.. References.. 4 Aerobic Solid-State Fermentation.. 4.1 Biology and Physics Foundation of Aerobic Solid-State Fermentation.. 4.1.1 Introduction to Aerobic Solid-State Fermentation.. 4.1.2 Aerobic Microorganisms and Nutrition.. 4.1.3 Physical Chemistry Foundations of Aerobic Solid Fermentation.. 4.2 Mixed Solid-State Fermentation.. 4.2.1 Overview.. 4.2.2 Process Principles.. 4.2.3 Process Evaluation.. 4.2.4 Key Technologies.. 4.2.5 Application of Mixed Solid-State Fermentation.. 4.3 Static Closed Solid-State Fermentation.. 4.3.1 Tray Solid-State Fermentation Technology.. 4.3.2 Packed Bed Aerobic Solid-State Fermentation Technology.. 4.4 Dynamic Solid-State Fermentation.. 4.4.1 Rotating Drum Aerobic Solid-State Fermentation Technology

4.4.2 Gas-Solid Fluidized Bed Fermentation.. 4.4.3 Gas Double Dynamic Solid-State Fermentation Technology.. 4.5 Numerical Simulation of the Fermentation Process Under Different Operating Conditions.. 4.5.1 Boundary Conditions and Control Equations for Tray Solid-State Fermentation.. 4.5.2 Boundary Conditions and Control Equations for Forced Ventilation Solid-State Fermentation.. 4.5.3 Boundary Conditions and Control Equations of Gas Double Dynamic Solid-State Fermentation.. 4.5.4 Numerical Simulation of Cellulase Production in Different Solid-State Fermentation Operating Modes.. References.. 5 Anaerobic Solid-State Fermentation.. 5.1 Biology and Physics Basis of Anaerobic Solid-State Fermentation.. 5.1.1 Similarities and Differences of Anaerobic and Aerobic Solid-State Fermentation.. 5.1.2 Biological Basis of Anaerobic Solid-State Fermentation.. 5.1.3 Physics Foundations of Anaerobic Solid-State Fermentation.. 5.2 Types of Anaerobic Solid-State Fermentation.. 5.2.1 Mixed Fermentation.. 5.2.2 Pure Culture Fermentation.. 5.3 Anaerobic Solid-State Fermentation Reactor.. 5.3.1 Ethanol Fermentation Reactor.. 5.3.2 Biogas Dry Fermentation Reactor.. 5.4 Application of Anaerobic Solid-State Fermentation.. 5.4.1 Application in Silage.. 5.4.2 Solid-State Anaerobic Treatment of Organic Solid Waste.. References.. 6 Principles and Application of Solid-State Fermentation Carried Out on Inert Support Materials (Adsorbed Carrier Solid-State Fermentation.. 6.1 Introduction to Solid-State Fermentation Carried Out on Inert Support Materials.. 6.1.1 Concept.. 6.1.2 Advantages.. 6.2 Material Properties of ACSSF.. 6.2.1 Material Characteristics of ACSSF.. 6.2.2 Types of Inert Carrier Materials.. 6.2.3 Inert Support Pretreatment.. 6.2.4 Growth Characteristics of Microorganisms on Inert Carriers.. 6.3 ACSSF Techniques and Fermentors.. 6.3.1 Packed Bed Bioreactor.. 6.3.2 Repeated Batch Bioreactor.. 6.3.3 Continuous Bioreactor

6.3.4 Horizontal Bioreactor.. 6.4 ACSSF Process Optimization.. 6.4.1 Effect of Moisture Content.. 6.4.2 Effect of Water Activity.. 6.4.3 Effect of Support Particle Size.. 6.4.4 Effect of Inert Carrier Depth.. 6.5 ACSSF Applications.. 6.5.1 Clavulanic Acid Production by SSF on PUF.. 6.5.2 Alkaline Protease Production by SSF on PUF.. 6.5.3 Clavulanic Acid Production by Continuous SSF on PUF.. 6.5.4 Xanthan Production by SSF on PUF.. 6.5.5 Bacterial Cellulose Production by SSF on PUF.. 6.6 Perspective on ACSSF.. 6.6.1 Economy of Commercial Systems.. 6.6.2 Challenges in ACSSF.. References.. 7 Development Trends and Application Prospects for Modern Solid-State Fermentation.. 7.1 Development Trends for Modern Solid-State Fermentation.. 7.1.1 In-Depth Knowledge of the Nature of Solid-State Fermentation.. 7.1.2 Research and Application of Online Monitoring Technology in Solid-State Fermentation.. 7.1.3 Solid-State Fermentation Equipment Design and Manufacture.. 7.1.4 Application of Mixed Culture in Solid-State Fermentation.. 7.1.5 Multidisciplinary Crossing in Solid-State Fermentation.. 7.2 Application Prospects for Modern Solid-State Fermentation.. 7.2.1 Introduction.. 7.2.2 Applicability of Solid Biomass Used as Substrate.. 7.2.3 Biomass Bioconversion Technology Based on Solid-State Fermentation.. References

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"Modern Solid State Fermentation: Theory and Practice" covers state-of-the-art studies in the field of solid state fermentation (SSF). In terms of different characteristics of microbial metabolites, this book catalogs SSF into two main parts: anaerobic and aerobic SSF. Based on the principles of porous media and strategies of process control and scale-up, which are introduced in the book, it not only presents a well-founded explanation of essence of solid state fermentation, but also their influence on microbial physiology. In addition, due to the rapid development of this field in recent years, inert support solid state fermentation is also examined in detail. At last, the modern solid state fermentation technology platform is proposed, which will be used in solid biomass bioconversion. This book is intended for biochemists, biotechnologists and process engineers, as well as researchers interested in SSF. eng

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