Colon cancer is a multifactorial disease whose progression is associated with the gradual accumulation of genetic and epigenetic mutations, besides exogenous factors such chronic inflammation, oxidative stress or eating habits. It has been proposed that plant-based foods like fruits, cereals, and legumes can inhibit carcinogenesis, especially colon carcinogenesis, due to the presence of fiber, protein, and various secondary metabolites, which can inhibit carcinogenic lesions in early stages, induce apoptosis, increase the activities of antioxidant enzymes and the concentration of short-chain fatty acids in the colon. As well as modulate the metabolism of carcinogenic compounds. In this work, a compilation of the advantages of the consumption of legumes and some of the compounds present in them that can prevent chronicdegenerative diseases and specifically colon cancer was made.
Resúmen
El cáncer de colon es una enfermedad multifactorial cuya progresión está asociada con la acumulación gradual de mutaciones genéticas y epigenéticas, factores exógenos tales como la inflamación crónica, el estrés oxidativo o hábitos alimenticios. Se ha propuesto que los alimentos de origen vegetal como las frutas, los cereales y las leguminosas pueden inhibir la carcinogénesis, en especial la de colon, debido a la presencia de fibra, proteínas y diversos metabolitos secundarios, mismos que pueden inhibir lesiones carcinogénicas en etapas tempranas, inducir apoptosis, aumento de las actividades de las enzimas antioxidantes, incrementar la concentración de ácidos grasos de cadena corta en el colon, así como modular el metabolismo de compuestos carcinógenos. En este trabajo, se realiza una recopilación de las ventajas que presenta el consumo de leguminosas y algunos de los compuestos presentes en la misma, en la prevención de enfermedades crónico-degenerativas y en específico de cáncer de colon.
Ene | Feb | Mar | Abr | May | Jun | Jul | Ago | Sept | Oct | Nov | Dic |
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22 | 18 | 48 | 34 | 31 | 43 | 34 | 20 | 17 | 19 | 14 | 5 |
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