Vista normal Vista MARC

Association of rs9939609-FTO with metabolic syndrome components among women from Mayan communities of Chiapas, Mexico

Núñez Ortega, Pilar Elena [autora] | Meneses, María E [autora] | Delgado Enciso, Iván [autor] | Irecta Nájera, César Antonio [autor] | Castro Quezada, Itandehui [autora] | Solís Hernández, Roberto [autor] | Flores Guillén, Leonides Elena [autora] | García Miranda, Rosario [autora] | Valladares Salgado, Adán [autor] | Locia Morales, Daniel [autor] | Ochoa Díaz López, Héctor [autor].
Tipo de material: Artículo en línea Artículo en línea Tipo de contenido: Texto Tipo de medio: Computadora Tipo de portador: Recurso en líneaTema(s): Síndrome metabólico | Mujeres indígenas | Polimorfismo de nucleótido simple | Indicadores demográficos | Antropometría | Anthropometry | Salud públicaTema(s) en inglés: Metabolic syndrome | Indigenous women | Single nucleotide polymorphism | Demographic indicator | Public healthDescriptor(es) geográficos: Chiapas (México) Nota de acceso: Disponible para usuarios de ECOSUR con su clave de acceso En: Journal of Physiological Anthropology. volumen 40, número 11 (December 2021), páginas 1-10. --ISSN: 1880-6791Número de sistema: 61509Resumen:
Inglés

Background: Metabolic syndrome (MetS) is a complex cluster of risk factors, considered as a polygenic and multifactorial entity. The objective of this study was to determine the association of rs9939609-FTO polymorphism and MetS components in adult women of Mayan communities of Chiapas. Methods: In a cross-sectional study, sociodemographic, anthropometric, clinical, and biochemical data were obtained from 291 adult women from three regions of Chiapas, Mexico. The prevalence of MetS and the allele and genotype frequencies of the rs9939609-FTO were estimated. Multivariate logistic regression models were used to assess the association of the single nucleotide polymorphism (SNP) with each of the MetS components. Results: The MetS prevalence was 60%. We found a statistically signifcant association between rs9939609-FTO and hyperglycemia in the dominant model (OR 2.6; 95% CI 1.3–5.3; p=0.007). Conclusions: Women from Mayan communities of Chiapas presented a high prevalence of MetS and a relevant association of the FTO variant with hyperglycemia. This is the frst study carried out in these Mayan indigenous communities from Chiapas.

Recurso en línea: https://doi.org/10.1186/s40101-021-00259-9
Lista(s) en las que aparece este ítem: Trabajos académicos sobre mujeres
Etiquetas de esta biblioteca: No hay etiquetas de esta biblioteca para este título. Ingresar para agregar etiquetas.
Star ratings
    Valoración media: 0.0 (0 votos)
Existencias
Tipo de ítem Biblioteca actual Colección Signatura Estado Fecha de vencimiento Código de barras
Artículos Biblioteca Electrónica
Recursos en línea (RE) 		ECOSUR Recurso digital ECO400000061509

Disponible para usuarios de ECOSUR con su clave de acceso

Background: Metabolic syndrome (MetS) is a complex cluster of risk factors, considered as a polygenic and multifactorial entity. The objective of this study was to determine the association of rs9939609-FTO polymorphism and MetS components in adult women of Mayan communities of Chiapas. Methods: In a cross-sectional study, sociodemographic, anthropometric, clinical, and biochemical data were obtained from 291 adult women from three regions of Chiapas, Mexico. The prevalence of MetS and the allele and genotype frequencies of the rs9939609-FTO were estimated. Multivariate logistic regression models were used to assess the association of the single nucleotide polymorphism (SNP) with each of the MetS components. Results: The MetS prevalence was 60%. We found a statistically signifcant association between rs9939609-FTO and hyperglycemia in the dominant model (OR 2.6; 95% CI 1.3–5.3; p=0.007). Conclusions: Women from Mayan communities of Chiapas presented a high prevalence of MetS and a relevant association of the FTO variant with hyperglycemia. This is the frst study carried out in these Mayan indigenous communities from Chiapas. eng

Con tecnología Koha