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Polychlorinated biphenyls (PCBs) : mammalian and environmental toxicology Libro electrónico editor: Stephen Safe

Tipo de material: Libro en línea Libro en línea Idioma: Inglés Series Detalles de publicación: New York, New York, United States Springer-Verlag c1987Descripción: x, 152 páginas ilustraciones 25 centímetrosISBN:
  • 0387155503
  • 9783642705526 (Print)
  • 9783642705502 (Online)
Tema(s) en español: Recurso en línea: Formatos físicos adicionales disponibles:
  • Disponible en línea
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Nota de acceso: Disponible para usuarios de ECOSUR con su clave de acceso Resumen:
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Polychlorinated biphenyls (PCBs) have been produced commercially since be­ fore 1930. They proved to be highly versatile mixtures and their uses continued to expand during the early 1970's even after the unanticipated world-wide en­ vironmental contamination had been discovered (Jensen et aI. , 1969; Koeman et aI. , 1969). Over 600,000 metric-tons were produced and/or used in the U. S. during this time and it is estimated that worldwide production totaled about 1,200,000 metric-tons (Table 1). With low acute toxicities (Fishbein, 1974), these mixtures were considered gen­ erally biologically inactive even though industrial exposure had demonstrated he­ patic and dermatological effects (Fishbein, 1974; Hansen, 1987). Thus, use and disposal were not carefully monitored and it is estimated that one-third of the world-wide production of PCBs has been released into the global environment (Table 1). Table 1. Estimated production and disposition of PCBs b U. s. a Worldwide 6 6 Production/use 610 X 10 kg 1200 X 10 kg Mobil environmental reservoir 82 400 Static reservoirs In service 340 Dumps 130 Total static 470 800 a NAS, 1979 b Tatsukawa and Tanaba, 1984 2 Environmental Distribution Many countries now impose strict controls on the use and release of PCBs. Re­ lease into the environment has declined dramatically in the last decade, but con­ tinued release from reservoirs (Table 1) into burdened ecosystems (Table 2) ap­ pears inevitable for several more decades (Barros et aI. , 1984).

Número de sistema: 56081
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Libros Biblioteca Electrónica Recursos en línea (RE) Acervo General Recurso digital ECO400560813122

Incluye bibliografía e índice: páginas 147-152

1. Polychlorinated biphenyls: environmental occurrence and analysis.. 2. Environmental toxicology of polychlorinated biphenyls.. 3. Mammalian biologic and toxic effects of PCBS.. 4. Carcinogenic and mutagenic effects of PCBS.. 5. Biotransformation of PCBS: metabolic pathways and mechanisms.. 6. Physiologic pharmacokinetic modeling of polychlorinated biphenyls.. 7. PCBS and human health.. Subject Index

Disponible para usuarios de ECOSUR con su clave de acceso

Polychlorinated biphenyls (PCBs) have been produced commercially since be­ fore 1930. They proved to be highly versatile mixtures and their uses continued to expand during the early 1970's even after the unanticipated world-wide en­ vironmental contamination had been discovered (Jensen et aI. , 1969; Koeman et aI. , 1969). Over 600,000 metric-tons were produced and/or used in the U. S. during this time and it is estimated that worldwide production totaled about 1,200,000 metric-tons (Table 1). With low acute toxicities (Fishbein, 1974), these mixtures were considered gen­ erally biologically inactive even though industrial exposure had demonstrated he­ patic and dermatological effects (Fishbein, 1974; Hansen, 1987). Thus, use and disposal were not carefully monitored and it is estimated that one-third of the world-wide production of PCBs has been released into the global environment (Table 1). Table 1. Estimated production and disposition of PCBs b U. s. a Worldwide 6 6 Production/use 610 X 10 kg 1200 X 10 kg Mobil environmental reservoir 82 400 Static reservoirs In service 340 Dumps 130 Total static 470 800 a NAS, 1979 b Tatsukawa and Tanaba, 1984 2 Environmental Distribution Many countries now impose strict controls on the use and release of PCBs. Re­ lease into the environment has declined dramatically in the last decade, but con­ tinued release from reservoirs (Table 1) into burdened ecosystems (Table 2) ap­ pears inevitable for several more decades (Barros et aI. , 1984). Inglés

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